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So far Doug Bailey has created 72 blog entries.

Solving Retention Time Drift in HPLC

By |2026-03-08T21:40:04-06:00January 18th, 2026|

HPLC Retention Time Drift: Troubleshooting Instability and Achieving Stable Retention Times High-Performance Liquid Chromatography (HPLC) is a cornerstone of modern analytical chemistry. However, achieving accurate and reliable results hinges on one crucial factor: stable retention times. HPLC retention time drift, the unwelcome change in the time it takes for a compound to [...]

EPA Ammonia Standards

By |2026-03-08T21:40:00-06:00January 16th, 2026|

EPA Ammonia Testing Standards: A Guide to Method 350.1 & NPDES Compliance Introduction: The Importance of Regulatory Compliance For municipal and industrial wastewater laboratories, accuracy is not just a scientific goal. It is a legal requirement. Under the Clean Water Act, ammonia is a regulated pollutant because of its proven toxicity to [...]

Choosing an Ammonia Analyzer

By |2026-03-08T21:39:56-06:00January 14th, 2026|

How to Choose the Best Ammonia Analyzer: Lab vs. Portable & Technology Comparison Introduction: Defining “Best” in Ammonia Analysis Choosing the best ammonia analyzer is not about finding one universally perfect instrument. It is about matching the right technology to your real testing conditions. If you are looking to buy an ammonia [...]

Ammonia vs Nitrate Analyzers

By |2026-03-08T21:39:46-06:00January 12th, 2026|

Ammonia vs. Nitrate Analyzers: Understanding the Difference and Selecting the Right Technology Introduction: The Nitrogen Speciation Challenge In water and wastewater testing, few topics cause as much confusion as nitrogen measurement. Many operators ask the same question: Is measuring Total Nitrogen enough? Often, the answer is no. This confusion usually shows up [...]

Gas Diffusion Technology: The “Dirty” Sample Solution

By |2026-03-08T21:39:42-06:00January 9th, 2026|

Gas Diffusion Technology: A Deep Dive into High-Performance Ammonia Analysis For decades, laboratory scientists have searched for the "holy grail" of ammonia measurement. The ideal solution needs to be fast, fully automated, and—most importantly—immune to the interference caused by dirty, complex, and variable samples. In the real world, water is rarely just [...]

Ammonia Analyzer Basics: The Complete Lab Guide

By |2026-03-08T21:39:37-06:00January 5th, 2026|

Ammonia Analyzer Basics: The Complete Guide to Laboratory Ammonia Testing In the intricate world of environmental science and industrial process control, few parameters are as critical—or as tricky—as ammonia. Understanding the levels of ammonia in water and soil is a daily necessity for scientists, environmental engineers, and wastewater treatment operators. From ensuring [...]

Green HPLC: Reducing Solvents via Temperature Control

By |2026-03-08T21:39:28-06:00January 2nd, 2026|

Green HPLC Methods: Reducing Solvents via Temperature Control The world of analytical chemistry is currently undergoing a massive transformation. For decades, the primary focus of any laboratory was simple: get the results. The method didn't matter, the cost was secondary, and the waste generated was just a cost of doing business. But [...]

Accelerating Analysis with High-Temperature HPLC

By |2026-03-08T21:39:32-06:00December 31st, 2025|

High Throughput HPLC: Accelerating Analysis with High-Temperature Liquid Chromatography "Time is money." In the modern analytical laboratory, this phrase is not merely a cliché; it is the governing reality that dictates daily operations, budget approvals, and strategic planning. Lab managers across pharmaceutical, environmental, and industrial sectors operate under relentless pressure to increase [...]

The Hidden Impact of Thermal Mismatch

By |2026-03-08T21:39:19-06:00December 29th, 2025|

The Hidden Impact of Thermal Mismatch: Why Your Mobile Phase Needs Pre-Heating In the high-stakes world of High-Performance Liquid Chromatography (HPLC), data integrity is everything. Laboratories around the globe invest hundreds of thousands of dollars in precision pumps, hyper-sensitive detectors, and state-of-the-art columns. The goal is simple: to ensure that every peak [...]

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