Timberline TL-600 Mobile Phase Pre-heater
Key Benefits
Increases Preparative Chromatography Yields by Improving Column Efficiencies
Improves Retention Time Reproducibility
Compact and Convenient, Replaces Troublesome Water Baths
Safe And Efficient, Thermal Fused For Failsafe Operation
The Timberline TL- 600 Mobile Phase Heater is used to heat the mobile phase before it enters a semi-preparative or preparative HPLC column. The advantages of operating at elevated column temperatures are plentiful. It has been shown that lowering mobile phase viscosity by operating at elevated temperatures can enhance column efficiency. Controlling column temperature improves retention time reproducibility for individual sample components. Achieving higher column efficiencies and maintaining retention time stability results in higher yields for preparative HPLC systems.
The TL-600 accommodates mobile phases flowing as fast as 100mL/min and temperatures as high as 80°C. The heating unit consists of two lengths of tubing cast into a solid metal block. The metal alloy block provides excellent temperature stability and efficient heat transfer. The tubing is coiled in a unique pattern that minimized the size and weight of the unit and reduces band broadening. One coil effectively heats mobile phases flowing from 10 - 50 mL/min. For higher flowrates, 20 - 100mL/min, the two coils are connected in series for increased heating capacity.
The electronics for temperature control are housed in a separate case, away from the heated block, to ensure years of trouble free operations. The control unit displays the actual temperature and the set point. This calibrated temperature controller keeps temperature of coils within ±0.1°C of the set point. The control unit will shut power off to heaters if temperature exceeds fuse rating, protecting laboratory, column, etc from excessive temperatures
Column temperature control for columns exceeding 1" in diameter is primarily achieved by controlling the inlet temperature of the mobile phase. From a heat transfer point of view heating the exterior of the column can not control the internal temperature of a larger ID column. For example, if a 1" OD SS column body is heated and room temperature mobile phase is flowing at 20 - 40mL/min, the temperature of the packing at column inlet would be between 10 to 20°C lower then the temperature at the column outlet. Insulating the column body and using the TL-600 to heat the mobile phase before it enters the column eliminates this temperature gradient.
Performance
The TL-600 easily heats 50mL/min aqueous mobile phase to 80°C. The actual mobile phase temperature at the outlet of the TL-600 is within 2°C of the controller setpoint. The pressure drop is only 50psig. At 100mL/min, the pressure drop would be 200psig.
Specifications
Temperature Range | Ambient+5°C to 80°C |
Temperature Stability | ± 0.1°C |
Heater Unit Case Dimensions | 5.25"H x 8.625"W x 13.5"D |
Controller Case Dimensions | 3.25"H x 8"W x 8.625"D |
Tubing Coil Dimensions | 1/16"OD x 0.04"ID x 20'Long |
Tubing Material | 316 Stainless Steel, Hastelloy C® |
Heaters | 600 W, 800W, Custom Wattages Available |
Controller Operating Voltage | 120VAC or 240VAC, selectable |
Ordering Information
Auto Samplers | Catalog Number |
TL-600, 600W, 120VAC, 2 each 20' SS Coils | 2606-1 |
TL-600, 600W, 120VAC, 2 each 20' Hastelloy C Coils | 2626-1 |
TL-600, 800W, 120VAC, 2 each 20' SS Coils | 2608-1 |
TL-600, 800W, 120VAC, 2 each 20' Hastelloy C Coils | 2628-1 |